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Ophthalmology

COSOPT Eye Drops SPC: Uses, Administration, Safety

Quick summary COSOPT 20 mg/ml + 5 mg/ml eye drops is a prescription combination of dorzolamide hydrochloride and timolol maleate. It is used to help reduce elevated intraocular pressure in open-angle glaucoma and ocular...

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Medical disclaimer

This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.

Quick summary

COSOPT 20 mg/ml + 5 mg/ml eye drops is a prescription combination of dorzolamide hydrochloride and timolol maleate. It is used to help reduce elevated intraocular pressure in open-angle glaucoma and ocular hypertension. Correct administration and regular follow-up are important.

Medical disclaimer

This article summarizes SPC-style information and is not a substitute for the official patient leaflet, product information, or advice from a qualified healthcare professional. Do not use this page to diagnose a condition or to change any treatment plan.

What is COSOPT 20 mg/ml + 5 mg/ml eye drops?

COSOPT is an eye drop solution that combines two active ingredients: dorzolamide hydrochloride and timolol maleate. The combination is used to help lower raised pressure inside the eye.

The original content describes COSOPT as a treatment option for patients who may not achieve enough pressure reduction with a single medicine alone.

What is COSOPT used for?

COSOPT is indicated for the treatment of elevated intraocular pressure in:

  • Open-angle glaucoma
  • Ocular hypertension

It is generally used when a healthcare professional considers that pressure control needs more than one active ingredient.

How is COSOPT administered?

Use the drops exactly as directed by the prescriber or pharmacist. The original content highlights the following general administration steps:

  1. Wash your hands before use.
  2. Tilt your head back and pull down the lower eyelid to form a small pocket.
  3. Instill one drop into the eye as directed.
  4. Close the eye and press gently on the inner corner for a short time to reduce drainage.
  5. Avoid touching the dropper tip to the eye, fingers, or any surface.

If more than one eye medicine is being used, the original content advises waiting at least 10 minutes before applying the next drop.

What strength is COSOPT?

The formulation described in the source content contains:

Active ingredient Strength
Dorzolamide hydrochloride 20 mg/ml
Timolol maleate 5 mg/ml

The original content states that the usual dose is one drop in the affected eye or eyes twice daily, but any dosing schedule should be confirmed with the official leaflet or a healthcare professional.

Who should not use COSOPT?

The source content lists several situations where COSOPT is contraindicated or may not be suitable. These include:

  • Known hypersensitivity to any component of the formulation
  • Severe respiratory conditions such as asthma or COPD
  • Bradycardia or other significant heart conditions

Pregnant or breastfeeding patients should discuss use with a healthcare professional before treatment.

What side effects are mentioned?

The original content mentions the following possible side effects:

  • Burning or stinging in the eye
  • Redness of the eye
  • Blurred vision

It also notes that more serious symptoms can occur and should be assessed promptly, including:

  • Difficulty breathing
  • Severe dizziness
  • Fainting spells

Any unusual or worrying symptom should be discussed with a healthcare professional.

What interactions should be checked?

The source content advises patients to tell their healthcare professional about all medicines they use, including:

  • Other eye drops
  • Prescription medicines taken by mouth
  • Over-the-counter products and supplements

Extra caution is mentioned for medicines that may lower heart rate or affect blood pressure, because of the timolol component.

Important note about availability

The original content states that COSOPT was withdrawn from the market as of 6 January 2021. If you are checking this product page for reference, confirm current availability and any alternatives with an official source, pharmacist, or prescriber.

Frequently asked questions

▸ What conditions is COSOPT used for?

The source content says COSOPT is used for elevated intraocular pressure in open-angle glaucoma and ocular hypertension.

▸ How should COSOPT eye drops be applied?

Wash your hands, place the drop into the lower eyelid pocket, avoid touching the dropper tip, and follow the directions given by the prescriber or leaflet.

▸ What side effects are mentioned in the source?

The content mentions burning or stinging, eye redness, blurred vision, and more serious symptoms such as breathing difficulty, severe dizziness, or fainting.

▸ Can COSOPT be used with other eye medicines?

The source content says to wait at least 10 minutes between different eye medicines. A healthcare professional should confirm the correct schedule.

▸ Is COSOPT still available?

The original content says it was withdrawn from the market on 6 January 2021. Availability should be checked through official or local sources.

Safety reminder

If you have eye pain, breathing problems, fainting, severe dizziness, or any sudden change in vision, seek urgent medical advice. Always check the official leaflet and speak with a healthcare professional for product-specific guidance.

Editorial note Active Ingredients Online Editorial Team This article is prepared as educational medicine information for general readers. It is written to support understanding of active ingredients, medicine uses, possible side effects, precautions and safety-related questions.
Published: March 3, 2025 Updated: May 12, 2026 Educational content

Medical disclaimer

This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.

Sources and verification

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Final note

Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.

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