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Prescription Drugs

Stalevo 100 mg/25 mg/200 mg Tablets | SPC

Quick summary: Stalevo 100 mg/25 mg/200 mg film-coated tablets are a prescription medicine used in adults with Parkinson’s disease. It combines levodopa, carbidopa and entacapone in one tablet to help manage motor symptoms and...

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Medical disclaimer

This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.

Quick summary: Stalevo 100 mg/25 mg/200 mg film-coated tablets are a prescription medicine used in adults with Parkinson’s disease. It combines levodopa, carbidopa and entacapone in one tablet to help manage motor symptoms and fluctuations.

This page is a plain-language summary of the product information. Always check the official leaflet and follow advice from a doctor or pharmacist.

Medical disclaimer: This article is for general information only and does not replace the official Summary of Product Characteristics (SPC), patient leaflet, or advice from a qualified healthcare professional. Do not use it to diagnose a condition or decide on treatment changes.

What is Stalevo 100 mg/25 mg/200 mg?

Stalevo 100 mg/25 mg/200 mg film-coated tablets are a prescription medicine used primarily for managing symptoms of Parkinson’s disease in adults. The product is manufactured by Orion Pharma (Ireland) Ltd.

It is a combination tablet designed to support treatment when Parkinson’s symptoms fluctuate. The medicine brings together three active ingredients in one dose.

What does Stalevo contain?

Stalevo contains the following active ingredients:

  • Levodopa – a precursor to dopamine.
  • Carbidopa – helps prevent levodopa from being converted too early outside the brain.
  • Entacapone – helps prolong the effect of levodopa by reducing its breakdown.

Together, these ingredients are intended to improve the delivery and duration of levodopa’s effect in the body.

How Stalevo is used

Stalevo is used as part of treatment for Parkinson’s disease, particularly where symptom control varies between doses. The aim is to help improve motor function and reduce “off” periods between doses.

The exact place of Stalevo in a treatment plan depends on the individual patient and the prescriber’s assessment.

Dosage information

The current product strength is 100 mg/25 mg/200 mg. The original content notes that dosing may vary depending on patient needs and response to treatment.

Because this is a prescription medicine, the dose and schedule should be taken exactly as directed by the prescriber. If you are checking a pack or leaflet, confirm the strength, timing, and any special instructions before use.

Topic What the content says
Strength 100 mg / 25 mg / 200 mg
Use Parkinson’s disease symptom management
Form Film-coated tablets
Manufacturer Orion Pharma (Ireland) Ltd

How to take Stalevo

The original content states that the tablet should be swallowed whole with water and not crushed or chewed. It also notes that consistent timing is important.

It may be taken with or without food, but the content advises avoiding high-protein meals close to dosing because this may affect levodopa absorption.

For practical use, patients should follow the instructions on the prescription label and the official leaflet.

Possible side effects

Like all medicines, Stalevo may cause side effects. The original content lists the following as common or possible effects:

  • Nausea and vomiting
  • Dizziness or light-headedness
  • Fatigue
  • Changes in mood or behaviour
  • Uncontrolled movements
  • Changes in blood pressure
  • Severe allergic reactions

If any unusual or concerning symptoms occur, the original content advises contacting a healthcare professional promptly.

What to know about the 200 mg strength

The original content mentions that Stalevo 200 mg is another formulation that may be used when a higher levodopa dose is needed. It also notes that dosing schedules may differ between formulations.

If you are comparing strengths, check the exact tablet strength on the pack and confirm the intended regimen with the prescriber or pharmacist.

How Stalevo may help

Stalevo is described as helping to increase dopamine availability in the brain by combining levodopa with carbidopa and entacapone. This may help with:

  • Motor function
  • Tremor control
  • Reducing “off” time between doses
  • Daily functioning and quality of life

Response can vary from person to person, and treatment monitoring is important.

What to verify with a doctor or pharmacist

If you are reading this page to understand a prescription or product label, it is sensible to confirm the following with a healthcare professional or the official leaflet:

  • The exact strength prescribed
  • When and how the tablets should be taken
  • Whether food timing matters for your regimen
  • What side effects should be reported
  • Whether any other medicines may affect treatment

Frequently asked questions

▸ What is Stalevo used for?

Stalevo is used in adults for managing symptoms of Parkinson’s disease, especially when motor symptoms fluctuate between doses.

▸ What ingredients are in Stalevo?

It contains levodopa, carbidopa and entacapone.

▸ Can Stalevo be taken with food?

The original content says it may be taken with or without food, but high-protein meals close to dosing may interfere with levodopa absorption.

▸ What side effects are mentioned?

The content mentions nausea, vomiting, dizziness, fatigue, mood or behaviour changes, uncontrolled movements, blood pressure changes and severe allergic reactions.

▸ Should the tablet be crushed or chewed?

No. The original content says the tablet should be swallowed whole with water.

▸ Where can I confirm the correct dose?

Check the prescription label, the official patient leaflet, or ask a doctor or pharmacist.

Safety reminder: If you have questions about side effects, timing, food interactions, or whether this medicine is suitable for you, speak to a doctor or pharmacist and refer to the official product leaflet. Do not change how you take a prescription medicine without professional advice.

Editorial note Active Ingredients Online Editorial Team This article is prepared as educational medicine information for general readers. It is written to support understanding of active ingredients, medicine uses, possible side effects, precautions and safety-related questions.
Published: March 25, 2025 Updated: May 12, 2026 Educational content

Medical disclaimer

This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.

Sources and verification

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Final note

Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.

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