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Panadol Night Film-coated Tablets: PIL Guide

Quick summary Panadol Night film-coated tablets combine paracetamol 500 mg with diphenhydramine 25 mg. They are intended for night-time pain relief when pain is affecting sleep. Medical disclaimer This article is a general guide...

Educational content Use this article as a starting point for understanding the topic.
Check with a professional Ask a doctor or pharmacist before changing any medicine.
Safety first Side effects, interactions and risks depend on each person.
Medical disclaimer

This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.

Quick summary

Panadol Night film-coated tablets combine paracetamol 500 mg with diphenhydramine 25 mg. They are intended for night-time pain relief when pain is affecting sleep.

Medical disclaimer

This article is a general guide based on the product information leaflet. It does not replace the official leaflet, a pharmacist’s advice, or medical care. If you are unsure whether this medicine is suitable for you, check with a healthcare professional.

Panadol Night is commonly used when pain makes it harder to settle at night. Because it contains a sedating ingredient, it may help with drowsiness as well as pain relief. However, it is not a general treatment for insomnia.

What are Panadol Night film-coated tablets?

Panadol Night film-coated tablets contain two active ingredients: paracetamol and diphenhydramine. Paracetamol is used for pain relief, while diphenhydramine is an antihistamine with sedating effects.

Together, these ingredients are designed for night-time use when pain and discomfort may interfere with sleep.

Is Panadol Night a sleeping tablet?

Panadol Night is not primarily a sleeping tablet. It is a pain relief medicine that also contains a sedating ingredient. That means it may help you feel sleepy, but its main purpose is to relieve pain at night.

If sleep problems continue without pain, it is sensible to ask a pharmacist or doctor about the right approach rather than using a pain relief medicine for sleep alone.

What is the active ingredient in Panadol Night?

The active ingredients listed in the leaflet are:

  • Paracetamol 500 mg
  • Diphenhydramine 25 mg

Always check the pack and leaflet, as product names and formulations can vary by country or manufacturer.

What is Panadol Night used for?

According to the leaflet-style information in the original content, Panadol Night is used for night-time pain relief. It may be used for common pains such as headache, toothache, and rheumatic pain when sleep is being affected.

It is best to confirm the exact uses on the official product leaflet for your local version of the medicine.

How is Panadol Night taken?

The original content states that the usual direction for adults and children over 12 years is 2 tablets before bedtime. It also says not to exceed 4 doses in 24 hours.

Because instructions can differ by country and pack size, always follow the directions on your own pack or the official leaflet.

Topic Information from the original content
Active ingredients Paracetamol 500 mg and diphenhydramine 25 mg
Main purpose Night-time pain relief with a sedating effect
Typical age group mentioned Adults and children over 12 years
Original dosing note 2 tablets before bedtime; do not exceed 4 doses in 24 hours

What are the side effects of Panadol Night?

The original content lists several possible side effects. These include:

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Confusion, especially in older adults
  • Allergic reactions

If you notice severe symptoms such as swelling of the face or difficulty breathing, seek urgent medical help.

How long does Panadol Night make you sleep?

The original content says the sedating effect of diphenhydramine may begin within about 30 minutes to an hour, but the length of sleep can vary from person to person.

Factors such as pain level, general health, and individual response can affect how sleepy you feel and how long you sleep.

Is Panadol Night safe for everyone?

Panadol Night is described in the original content as generally suitable for adults and children over 12 years, but not necessarily for everyone.

Extra caution is mentioned for people with liver disease, pregnant or breastfeeding women, and older adults, because the sedating ingredient may affect them more strongly.

If you take other medicines or have an ongoing health condition, it is sensible to check the leaflet and ask a pharmacist or doctor for advice.

Panadol vs Panadol Night

The main difference described in the original content is that Panadol contains paracetamol for pain relief, while Panadol Night adds diphenhydramine to help with drowsiness at night.

That makes Panadol Night more focused on night-time pain that may disturb sleep.

Frequently asked questions

▸ Is Panadol Night a sleeping pill?

No. It is a pain relief medicine with a sedating ingredient. It may help you feel sleepy, but it is not mainly intended as a sleeping pill.

▸ What is the active ingredient in Panadol Night?

The original content states that it contains paracetamol 500 mg and diphenhydramine 25 mg.

▸ Who should not take Panadol Night?

The original content advises caution for people with certain health conditions, pregnant or breastfeeding women, and anyone taking other medicines that may interact. A pharmacist or doctor can help check suitability.

▸ What is the difference between Panadol and Panadol Night?

Panadol Night includes diphenhydramine, which adds a sedating effect. Standard Panadol is described as paracetamol-based pain relief without that night-time sedative component.

▸ Is one Panadol Night tablet enough?

The original content says the usual dose is 2 tablets, but individual response can vary. Follow the instructions on your pack and ask a pharmacist if you are unsure.

▸ How long does Panadol Night take to work?

The original content suggests drowsiness may begin within 30 minutes to an hour, though this can vary between people.

Safety reminder

Do not exceed the dose on the pack, and do not combine this medicine with other products that contain paracetamol unless a healthcare professional has told you it is safe. If pain continues, gets worse, or keeps disturbing your sleep, speak to a pharmacist or doctor.

Always read the patient information leaflet that comes with your specific pack before use.

Editorial note Active Ingredients Online Editorial Team This article is prepared as educational medicine information for general readers. It is written to support understanding of active ingredients, medicine uses, possible side effects, precautions and safety-related questions.
Published: March 5, 2025 Updated: May 12, 2026 Educational content

Medical disclaimer

This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.

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Final note

Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.

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