Nustendi 180mg/10mg Tablets: Uses, Side Effects & More
Quick summary: Nustendi 180mg/10mg film-coated tablets combine bempedoic acid and ezetimibe. They are used in adults to help manage high cholesterol, including hypercholesterolaemia and mixed dyslipidaemia. This overview explains what the medicine is for,...
This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.
Quick summary: Nustendi 180mg/10mg film-coated tablets combine bempedoic acid and ezetimibe. They are used in adults to help manage high cholesterol, including hypercholesterolaemia and mixed dyslipidaemia.
This overview explains what the medicine is for, how it works, common side effects, and practical points to check with a doctor or pharmacist.
Medical disclaimer: This article is for general information only and does not replace advice from a qualified healthcare professional. Always follow the official patient leaflet and the instructions given with your prescription.
What are Nustendi 180mg/10mg film-coated tablets?
Nustendi 180mg/10mg film-coated tablets are a prescription medicine used in adults to help manage hypercholesterolaemia and mixed dyslipidaemia. They contain two active ingredients: bempedoic acid and ezetimibe.
The combination is designed to lower cholesterol in two ways: by reducing cholesterol production in the liver and by reducing cholesterol absorption from the diet.
Nustendi may be considered for people who cannot tolerate statins or who need additional cholesterol-lowering treatment. It is also used in adults with established cardiovascular disease to help reduce cardiovascular risk.
How does Nustendi help lower LDL cholesterol?
Nustendi works through a dual mechanism.
Bempedoic acid
Bempedoic acid helps reduce cholesterol production in the liver by inhibiting ATP citrate lyase, an enzyme involved in cholesterol synthesis.
Ezetimibe
Ezetimibe helps lower cholesterol by reducing its absorption from the intestine.
Together, these actions can help lower LDL cholesterol, which is often called “bad” cholesterol. Your healthcare professional may monitor your lipid levels to see how well treatment is working.
Is Nustendi a statin?
No. Nustendi is not a statin medicine.
It lowers cholesterol using a different mechanism from statins. This is one reason it may be used in people who cannot tolerate statins or who need another option alongside existing treatment.
What are the side effects of Nustendi?
Like all medicines, Nustendi can cause side effects. The original content highlights gastrointestinal effects and muscle-related symptoms as important points to be aware of.
- Nausea
- Diarrhoea
- Abdominal pain
- Muscle pain or weakness
Muscle-related symptoms are especially important to mention if Nustendi is used with a statin. If you notice unexplained muscle pain or weakness, seek medical advice promptly.
People with a history of liver problems, or those who are pregnant or breastfeeding, should discuss suitability with a healthcare professional before use.
What is the recommended dosage?
The original content states that the recommended dosage is one tablet once daily. Nustendi can be taken with or without food.
It is important to follow the directions on your prescription and the official patient leaflet. Do not change how you take the medicine without speaking to a healthcare professional.
If bile acid sequestrants are also being used, the original content notes that Nustendi should be taken at least 2 hours before or 4 hours after the bile acid sequestrant.
How can patients access Nustendi through pharmacies?
Nustendi is a prescription medicine, so a valid prescription from a licensed healthcare provider is needed. Pharmacies may offer in-person collection, online services, or delivery options depending on location and service availability.
If cost or supply is a concern, a pharmacist can help explain what is available locally and whether any coverage may apply.
What should patients check before using Nustendi?
| Check point | Why it matters |
|---|---|
| Current medicines | To help identify possible interactions, including with bile acid sequestrants. |
| History of liver problems | The original content notes this as an important safety consideration. |
| Pregnancy or breastfeeding | Suitability should be discussed with a healthcare professional. |
| Kidney concerns | The article notes that people with existing kidney conditions should seek medical advice. |
Frequently asked questions
▸ What are Nustendi tablets used for?
They are used in adults to help treat hypercholesterolaemia and mixed dyslipidaemia, and to help reduce cardiovascular risk in people with established cardiovascular disease.
▸ How does Nustendi lower LDL cholesterol?
It combines bempedoic acid, which reduces cholesterol production in the liver, with ezetimibe, which reduces cholesterol absorption from the intestine.
▸ Can Nustendi cause muscle pain?
Muscle pain or weakness is listed in the original content as a possible side effect. It is especially important to report if the medicine is used with a statin.
▸ When should Nustendi be taken?
The original content says it is taken once daily and can be taken with or without food. Consistency may help with routine and tolerability.
▸ Can Nustendi be taken with bile acid sequestrants?
Yes, but the original content says it should be taken at least 2 hours before or 4 hours after a bile acid sequestrant.
▸ Is Nustendi the same as sertraline?
No. Sertraline is a different medicine used for mental health conditions such as depression and anxiety disorders. It is unrelated to cholesterol treatment.
Safety reminder: If you have new or worsening symptoms, especially muscle pain, weakness, or concerns about liver or kidney health, speak to a healthcare professional or pharmacist and check the official patient leaflet.
Medical disclaimer
This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.
Sources and verification
The following sources or official references are listed to support verification of the medicine information discussed in this article.
- Nustendi Summary of Product Characteristics (SmPC)
- Nustendi Patient Information Leaflet (PIL)
- NHS: High cholesterol
- European Medicines Agency: Nustendi
To improve this article with specific references, add a custom field named _aio_sources in the post editor and write one source per line using: Source title|Source URL.
Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.