Gastrografin gastroenteral solution: SmPC summary

What is Gastrografin gastroenteral solution?

Gastrografin is a radiopaque contrast medium used in imaging of the gastrointestinal tract. It helps make the digestive tract more visible on X-ray-based examinations.

The solution contains sodium amidotrizoate and meglumine amidotrizoate. It may be used by mouth or by rectal administration, depending on the examination and clinical need.

It is used in situations where clear visualisation of the gastrointestinal tract is needed, including when barium sulfate may not be suitable.

How does Gastrografin work?

Gastrografin works because it is radiopaque, meaning it absorbs X-rays and outlines the gastrointestinal tract during imaging.

This can help healthcare professionals assess the location and appearance of the bowel and identify abnormalities such as obstruction, perforation, stenosis, or bleeding.

What is Gastrografin used for?

According to the original content, Gastrografin is used in gastrointestinal imaging for several diagnostic purposes.

• Evaluation of gastrointestinal obstruction
• Assessment of perforations
• Detection of acute haemorrhage
• Assessment of chronic bowel conditions such as Crohn’s disease and ulcerative colitis
• Planning of surgical or diagnostic procedures where bowel visualisation is important

Gastrografin and bowel obstruction

In bowel obstruction, Gastrografin may be used to outline the gastrointestinal tract on imaging and help show the site and extent of the blockage.

This can support clinical assessment and treatment planning. The exact use depends on the patient’s condition and the imaging protocol chosen by the healthcare team.

How is Gastrografin administered?

Gastrografin may be administered orally, rectally, or through a nasogastric (NG) tube, depending on the examination and the patient’s ability to take the solution.

When given through an NG tube, correct tube placement and careful monitoring are important. Administration should be carried out by trained healthcare professionals.

What is the dosage of Gastrografin?

The original content states that dosage varies according to age, weight, and the type of examination.

For adults, oral doses are described as typically ranging from 60 to 100 mL, while rectal administration may be up to 500 mL. Paediatric doses are adjusted individually.

Because the exact dose depends on the procedure and the patient, the official product information and local clinical guidance should always be checked.

What are the side effects of Gastrografin?

As with other contrast media, Gastrografin may cause side effects. The original content lists the following:

• Nausea
• Vomiting
• Abdominal discomfort
• Headache
• Allergic reactions such as hives

Severe allergic reactions can occur in some cases, including shortness of breath or swelling. Patients are usually monitored during and after administration, especially if they have a history of hypersensitivity.

What precautions should be taken?

Before Gastrografin is used, healthcare professionals should review the patient’s history and the planned procedure carefully.

• Check for known allergy to iodine or contrast media
• Monitor infants, older adults, and other vulnerable patients closely
• Use only under the supervision of qualified healthcare professionals
• Review other medicines and clinical factors that may affect safety

The original content also notes that interactions with other medicines may affect safety or effectiveness.

Composition of Gastrografin

Gastrografin contains two active ingredients:

• Sodium amidotrizoate
• Meglumine amidotrizoate

These ingredients provide the radiopaque effect needed for imaging.

Frequently asked questions