EMEND 80mg/125mg Capsules: PIL Information
Quick summary: EMEND 80mg and 125mg hard capsules contain aprepitant. They are used to help prevent nausea and vomiting linked to chemotherapy in adults and adolescents aged 12 years and over. This page summarises...
This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.
Quick summary: EMEND 80mg and 125mg hard capsules contain aprepitant. They are used to help prevent nausea and vomiting linked to chemotherapy in adults and adolescents aged 12 years and over.
This page summarises the patient leaflet information in a clear, easy-to-read format. Always check the official leaflet and speak with a healthcare professional if anything is unclear.
Medical disclaimer: This article is for general information only and does not replace the patient information leaflet, a pharmacist’s advice, or guidance from your doctor or oncology team. It is not a diagnosis or treatment plan.
What EMEND capsules are used for
EMEND 80mg and 125mg hard capsules are used to help prevent nausea and vomiting caused by chemotherapy.
The medicine is used in adults and adolescents aged 12 years and older. It is usually part of a wider anti-sickness treatment plan.
EMEND is not described here as a treatment for nausea from other causes. If you are unsure why it has been prescribed, check with your healthcare professional.
How EMEND works
The active ingredient in EMEND is aprepitant. It belongs to a group of medicines called NK1 receptor antagonists.
Aprepitant works by blocking the action of substance P, a chemical involved in nausea and vomiting signals in the brain. This helps reduce the chance of feeling sick around chemotherapy treatment.
EMEND is often used together with other anti-sickness medicines as part of a planned regimen.
How EMEND is usually taken
The exact schedule should always be followed as prescribed. The leaflet information commonly describes use around chemotherapy, with doses taken on specific days.
- 125 mg on the first day of chemotherapy
- 80 mg on the following days, if prescribed
Timing matters with this medicine, so it is important to follow the instructions given by the prescriber, pharmacist, or official leaflet.
Possible side effects
Like all medicines, EMEND can cause side effects. The leaflet information in the source content mentions the following:
- Fatigue
- Dizziness
- Headache
- Constipation
- Loss of appetite
Not everyone gets side effects, and some may be mild. If anything feels severe, persistent, or unusual, speak to a healthcare professional.
Seek urgent medical help if signs of a serious allergic reaction occur, such as swelling, rash, or difficulty breathing.
Precautions and important safety points
Before using EMEND, it is important to tell a healthcare professional about any medical conditions, especially liver disease.
The source content also notes that EMEND may interact with other medicines, including:
- Corticosteroids
- 5-HT3 antagonists
- Warfarin
- Anticonvulsants
Because interactions can affect how medicines work, it is important to share a full list of prescribed medicines, over-the-counter products, and supplements with your pharmacist or doctor.
Pregnant or breastfeeding people should discuss use with a healthcare professional before taking EMEND.
Pregnancy and breastfeeding
The source content states that EMEND should not be used during pregnancy without medical advice, because safety has not been established.
If you are pregnant, think you may be pregnant, or are breastfeeding, ask a healthcare professional to review the leaflet information and your treatment plan.
What to check with your doctor or pharmacist
If you have been prescribed EMEND, it can help to confirm the following:
- Which strength you should take and on which day
- Whether it should be taken with other anti-sickness medicines
- Whether any of your regular medicines may interact
- What to do if you miss a dose
- Whether your liver condition or pregnancy status changes the advice
These details should come from the official leaflet or your healthcare team.
Quick reference table
| Topic | Key point |
|---|---|
| Active ingredient | Aprepitant |
| Main use | Prevention of chemotherapy-related nausea and vomiting |
| Age group mentioned | Adults and adolescents aged 12 years and older |
| Commonly mentioned side effects | Fatigue, dizziness, headache, constipation, loss of appetite |
| Important caution | Possible interactions with other medicines and caution in liver disease |
Frequently asked questions
▸ What is EMEND 80mg/125mg used for?
EMEND is used to help prevent nausea and vomiting linked to chemotherapy in adults and adolescents aged 12 years and older.
▸ How does EMEND work?
It contains aprepitant, which blocks NK1 receptors and helps reduce nausea and vomiting signals in the brain.
▸ What side effects are mentioned for EMEND?
The source content lists fatigue, dizziness, headache, constipation, and loss of appetite. Serious allergic reactions need urgent medical help.
▸ Can EMEND interact with other medicines?
Yes. The source content mentions possible interactions with corticosteroids, 5-HT3 antagonists, warfarin, and anticonvulsants. Always check with a pharmacist or doctor.
▸ Is EMEND suitable in pregnancy or breastfeeding?
The source content says pregnancy safety has not been established, so medical advice is needed before use. Breastfeeding should also be discussed with a healthcare professional.
▸ What should I do if I am unsure how to take it?
Check the official patient leaflet and ask your pharmacist, doctor, or oncology team to confirm the correct schedule.
Safety reminder: Do not rely on this summary alone for treatment decisions. Always follow the instructions on your prescription and the official patient leaflet, and contact a healthcare professional promptly if you have side effects, possible interactions, or questions about use.
Medical disclaimer
This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.
Sources and verification
The following sources or official references are listed to support verification of the medicine information discussed in this article.
- EMEND 80 mg / 125 mg hard capsules – Patient Information Leaflet
- Aprepitant – Summary of Product Characteristics
- NHS medicines information: aprepitant
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Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.