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Yohimbine (Yohimbe): Uses, Warnings, and Side Effects

Quick summary Yohimbine is a medicine associated with treatment of erectile dysfunction. This article summarizes its main uses, reported interactions, warnings, and side effects based on the source content. Medical disclaimer: This page is...

Educational content Use this article as a starting point for understanding the topic.
Check with a professional Ask a doctor or pharmacist before changing any medicine.
Safety first Side effects, interactions and risks depend on each person.
Medical disclaimer

This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.

Quick summary

Yohimbine is a medicine associated with treatment of erectile dysfunction. This article summarizes its main uses, reported interactions, warnings, and side effects based on the source content.

Medical disclaimer: This page is for general information only and does not replace advice from a doctor, pharmacist, or official product leaflet. Do not use this article to diagnose a condition or to decide on treatment changes.

What is yohimbine?

Yohimbine is a drug used to treat erectile dysfunction. The ingredient mentioned in the source content is yohimbine hydrochloride (HCl).

Brand names listed in the source include Yohimbe, Yocon, Yoman, and Erex.

How yohimbine is described to work

The source content states that yohimbine may increase blood flow and nerve impulses to the penis or vagina.

For a full explanation of how a specific product works, readers should check the official leaflet or ask a healthcare professional.

Uses and reported benefits

The main use listed is erectile dysfunction.

The source also mentions use in sexual dysfunction associated with SSRI treatment.

Warnings and precautions

The source notes that products containing man-made yohimbine hydrochloride are not legal to sell as a dietary supplement in the United States.

The content also lists the following conditions as contraindications: diabetes, depression, anxiety, high blood pressure, kidney disease, liver disease, schizophrenia, pregnancy, and breast-feeding.

If any of these apply, a clinician or pharmacist should review the product information before use.

Interactions

The source lists several medicines that may interact with yohimbine.

Interaction group Examples listed in the source
Medicines for depression Phenelzine, tranylcypromine, amitriptyline, imipramine
Medicines for high blood pressure Captopril, enalapril, losartan, valsartan, diltiazem, amlodipine, hydrochlorothiazide, furosemide
Other medicines listed Chlorpromazine, fluphenazine, trifluoperazine, thioridazine, naloxone, clonidine, diethylpropion, epinephrine, phentermine, pseudoephedrine

Because interaction lists can change, readers should verify all medicines, supplements, and over-the-counter products with an official source or healthcare professional.

Dosage information in the source

The source gives a dose range of 15–30 mg/day for erectile dysfunction.

Dosage can vary by product and patient factors, so the official prescribing information should always be checked for the exact formulation being used.

Side effects reported in the source

The source lists the following side effects:

  • Excitation
  • Tremor
  • Sleep problems
  • Anxiety or agitation
  • High blood pressure
  • Racing heartbeat
  • Dizziness
  • Stomach problems
  • Chills
  • Listlessness
  • Itchy, scaly skin
  • Drooling
  • Sinus pain
  • Irritability
  • Headache
  • Frequent urination
  • Bloating
  • Rash
  • Nausea
  • Vomiting

What to verify before using any yohimbine product

Before using a product containing yohimbine, it is important to confirm:

  • the exact active ingredient and salt form
  • whether the product is a medicine or supplement
  • the official dosing instructions
  • possible interactions with current medicines
  • whether the product is appropriate for your health history

FAQ

▸ What is yohimbine used for?

The source content says yohimbine is used to treat erectile dysfunction and may also be used for SSRI-related sexual dysfunction.

▸ Is yohimbine the same as yohimbe?

The source lists Yohimbe as one of the brand names associated with yohimbine, but product names and ingredients should always be checked carefully on the label.

▸ What side effects are mentioned for yohimbine?

The source lists effects such as anxiety, tremor, sleep problems, high blood pressure, racing heartbeat, dizziness, stomach problems, nausea, and vomiting.

▸ Can yohimbine interact with other medicines?

Yes. The source lists interactions with several medicines for depression, high blood pressure, and other drugs such as pseudoephedrine and phentermine.

▸ Where can I check official information?

The FDA medication guide and other official drug information sources are the best places to confirm product-specific details.

Safety reminder

If you are considering a product containing yohimbine, review the official label and speak with a qualified healthcare professional, especially if you take other medicines or have a medical condition.

Sources and references

Editorial note Active Ingredients Online Editorial Team This article is prepared as educational medicine information for general readers. It is written to support understanding of active ingredients, medicine uses, possible side effects, precautions and safety-related questions.
Published: June 24, 2019 Updated: August 17, 2026 Educational content

Medical disclaimer

This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.

Sources and verification

The following sources or official references are listed to support verification of the medicine information discussed in this article.

Final note

Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.

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