Xigduo 5 mg/1,000 mg Tablets: Patient Information Guide
Quick summary: Xigduo 5 mg/1,000 mg film-coated tablets combine dapagliflozin and metformin to help manage type 2 diabetes in adults, alongside diet and exercise. This guide explains what the medicine is for, how it...
This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.
Quick summary: Xigduo 5 mg/1,000 mg film-coated tablets combine dapagliflozin and metformin to help manage type 2 diabetes in adults, alongside diet and exercise.
This guide explains what the medicine is for, how it works, common side effects, key precautions, storage, and questions to discuss with a doctor or pharmacist.
Medical disclaimer: This article is for general information only and does not replace the patient leaflet, a pharmacist’s advice, or guidance from a healthcare professional. Always check the official leaflet and speak to a clinician if you are unsure whether a medicine is suitable for you.
What is Xigduo 5 mg/1,000 mg?
Xigduo 5 mg/1,000 mg film-coated tablets are a prescription medicine used in adults with type 2 diabetes. It contains two active ingredients: dapagliflozin and metformin.
The medicine is used to help improve blood sugar control when diet and exercise alone are not enough. It may also be used with other diabetes treatments, depending on the treatment plan chosen by a healthcare professional.
How does Xigduo work?
Xigduo combines two medicines that work in different ways:
- Dapagliflozin helps the body remove extra glucose through the urine.
- Metformin helps reduce glucose production in the liver and improves the body’s response to insulin.
Using both ingredients together can help support better blood sugar control in type 2 diabetes.
What is Xigduo used for?
Xigduo is used for the management of type 2 diabetes in adults. It is intended to be used together with lifestyle measures such as:
- healthy eating
- regular physical activity
- ongoing blood sugar monitoring, where advised
The original leaflet content also notes that it may be considered when other antidiabetic treatment has not provided enough control.
Dosage and how it is taken
The content provided states that the usual starting dose may be one tablet once daily, but the exact dose and timing should always follow the prescriber’s instructions.
If you are checking the medicine for a patient, it is important to confirm the strength, dosing schedule, and whether it should be taken with food from the official leaflet or dispensing label.
| Topic | What to verify |
|---|---|
| Dose | Confirm the prescribed tablet strength and how often it should be taken. |
| Timing | Check whether it should be taken at the same time each day and whether food is recommended. |
| Monitoring | Ask what blood tests or glucose checks are needed during treatment. |
Warnings and precautions
The original content highlights several important precautions. Xigduo should not be used by people with a known allergy to dapagliflozin or metformin. It also notes that severe kidney impairment is an important concern.
Because metformin can be associated with lactic acidosis in rare situations, kidney function monitoring is important. A healthcare professional should review the full medical history before treatment is started.
- Tell a clinician about any kidney problems.
- Share a full list of medicines and supplements to check for interactions.
- Ask whether kidney function monitoring is needed.
- Report any history of lactic acidosis or allergy to the ingredients.
Possible side effects
Not everyone gets side effects. The content provided mentions the following possible effects:
- nausea
- vomiting
- diarrhoea
- urinary tract infections
- low blood sugar when used with other antidiabetic medicines
More serious symptoms may need urgent medical attention. The original content specifically mentions lactic acidosis as a rare but serious risk, with symptoms such as unusual muscle pain, difficulty breathing, and abdominal discomfort.
Storage and handling
Store the tablets in their original packaging, at room temperature, and protect them from direct sunlight and moisture. Keep all medicines out of the reach of children and pets.
If tablets are damaged or out of date, follow local medicine disposal guidance or ask a pharmacist how to dispose of them safely.
What to check with a doctor or pharmacist
If you are reviewing this medicine for yourself or a patient, the most useful checks are:
- the exact prescribed strength and dosing instructions
- whether the medicine should be taken with food
- any kidney-related monitoring requirements
- possible interactions with other diabetes medicines
- what to do if a dose is missed
Frequently asked questions
▸ What is Xigduo 5 mg/1,000 mg used for?
It is used to help manage type 2 diabetes in adults, alongside diet and exercise.
▸ What ingredients are in Xigduo?
It contains dapagliflozin and metformin.
▸ Does Xigduo cause weight loss?
The original content notes that some people may experience weight loss, but results can vary from person to person.
▸ What are the common side effects?
The content mentions nausea, vomiting, diarrhoea, urinary tract infections, and low blood sugar when used with other diabetes medicines.
▸ Who should not take Xigduo?
The original content says people with severe kidney impairment, a known allergy to dapagliflozin or metformin, or a history of lactic acidosis should avoid it.
▸ Where can I confirm the correct instructions?
Check the official patient information leaflet, the dispensing label, or ask a pharmacist or prescriber.
Safety reminder: If you notice severe symptoms, signs of an allergic reaction, or symptoms that could suggest lactic acidosis, seek urgent medical advice. Do not rely on this page alone for treatment decisions.
Medical disclaimer
This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.
Sources and verification
The following sources or official references are listed to support verification of the medicine information discussed in this article.
Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.