XYLOMETAZOLINE (Triaminic): What is used for?
[toc] What is Xylometazoline? Xylometazoline (Xilometazolina) is a drug used to treat nasal congestion. The product ingredientĀ is Xylometazoline hydrochloride (hcl). The brand names of Xylometazoline in the United States are: Otrivin, Triaminic Decongestant Nasal...
This content is for educational purposes only and does not replace medical advice, diagnosis or treatment from a qualified healthcare professional.
[toc]
What is Xylometazoline?
Xylometazoline (Xilometazolina) is a drug used to treat nasal congestion. The product ingredientĀ is Xylometazoline hydrochloride (hcl).
The brand names of Xylometazoline in the United States are: Otrivin, Triaminic Decongestant Nasal Spray & Sinus Congestion, Balminil Nasal Decongestant and 4-Way Moisturizing Relief.
Mechanism of action (MOA) of Xylometazoline
Stimulates alpha-adrenergic receptors, reduces congestion of the nasal mucosa by vasoconstriction.
Therapeutic indications, uses and benefits of Xylometazoline
Local and temporary relief of nasal congestion.
Dosage of Xylometazoline
Nasal:
Adults and children > 12 years: 1 application of sun. 0.1%/nasal fossa/8 h. Max. 3 days in a row.
Children ā„ 6 years: 1-2 drops of sun. 0.05 %/nose, 1 application daily. Max. 2 times/day.
Method of administrationĀ
It is convenient to carefully clean the nose before its administration.
ContraindicationsĀ
Hypersensitivity to this medicine or other adrenergic decongestants; increased intraocular pressure especially in narrow-angle glaucoma.
Patients who have had transsphenoidal hyperphysiectomy or some type of surgery with dura exposure; dry inflammation of the nasal mucosa (dry rhinitis).
Children < 12 years; atrophic or vasomotor rhinitis; patients treated with MAOI or have been treated in the previous 2 weeks, or with other medications with antihypertensive effect.
Warnings and precautionsĀ
Subjects that respond exaggeratedly to sympathomimetics, diabetes mellitus, high blood pressure, glaucoma, cardiovascular diseases, pheochromocytoma, metabolic disorders, hyperthyroidism, prostatic hypertrophy.
Concomitance with: maprotiline, adrenergic bronchodilators.
Prolonged or excessive use causes rebound nasal congestion.
Interactions
Do not use with: tricyclic antidepressants, phenothiazines, methyldopa.
Pregnancy
It should not be used, with the available data it is not possible to rule out fetal risk.
Breastfeeding
It is not known whether this medicine is excreted into breast milk.
Although no cases harmful to the newborn have been reported, the use of xylomethacoline during breastfeeding is not recommended as risk to the newborn cannot be ruled out.
Effects on ability to driveĀ
If the patient experiences drowsiness or dizziness, do not drive or operate dangerous machinery.
Adverse reactions and side effects of Xylometazoline
Rare: dryness, itching, itching and burning nose, sneezing; headache, nausea, dizziness.
āāāāā VIDEO OF XYLOMETAZOLINE/TRIAMINIC (DRUG)
Source: The content of this active ingredient has been written taking into account the clinical and molecular information of all medicines authorised and marketed in the United States under the Unique Ingredient Identifier (UNII) by the Substance Registration System (SRS) of the Food and Drug Administration (FDA) and the United States Pharmacopeia (USP).
In order to know in detail the information authorized by the FDA for each drug, you should consult the corresponding medication guide authorized by the FDA.
Resources:
UNII: WPY40FTH8KĀ
ChemIDplus
DrugPortal
PubChem CID: 5709
NCI Thesaurus: C87749
Medical disclaimer
This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.
Sources and verification
Medicine information can change by country, product formulation and official safety updates. For personal decisions, verify details with official medicine information and a qualified healthcare professional. These official resources can help readers check medicine safety information:
- U.S. Food and Drug Administration ā Drug information and safety updates
- MedlinePlus ā Medicines and supplements
- European Medicines Agency ā Medicines information
- NHS ā Medicines A to Z
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Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.