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GUAIFENESIN (Mucinex): What is used for?

[toc] What is Guaifenesin? Guaifenesin (Guaifenesina) is an active ingredient used to treat cough and runny nose. The brand names of Guaifenesin in the United States are: Mucinex, Robitussin Chest Congestion, Robafen, Tussin. Mechanism...

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[toc]

What is Guaifenesin?

Guaifenesin (Guaifenesina) is an active ingredient used to treat cough and runny nose.

The brand names of Guaifenesin in the United States are: Mucinex, Robitussin Chest Congestion, Robafen, Tussin.

Mechanism of action (MOA) 

Reduces viscosity and facilitates the elimination of secretions, increasing fluid expectoration in the respiratory tract.

Therapeutic indications, uses and benefits 

  • Respiratory conditions with expectoration.
  • Cough.

Dosage of Guaifenesin

Oral:

  • Syrup 20 mg/ml. Adults and children > 12 years: 10 ml 4 times/day.
  • Syrup 66.6 mg/5 ml. Adults and children > 12 years: 15 ml; children 6-11 years: 10 ml; every 4 or 6 h.
  • Syrup 0,65 g/100 ml. Adults: 15 ml; 3-4 times/day.

Drink a glass of water after each dose. Do not exceed recommended dose.

Contraindications

Hypersensitivity.

Warnings and precautions

  • Do not use in persistent or chronic cough due to asthma or when accompanied by excessive secretion, unless medically indicated.
  • Clinical evaluation if the cough persists after 7 days of treatment.
  • Severe liver or kidney disease; concomitant use with cough suppressants.

Interactions

False increase of 5-hydroxyindolacetic acid with nitroso-naphthol reagent and vanilmandelic acid, in urine.

To suppress administration 48 h before.

Pregnancy

Not recommended, insufficient information.

Breastfeeding

It is not known whether this medicine is excreted through breast milk.

Adverse reactions and side effects 

Gastrointestinal discomfort, nausea, vomiting; hypersensitivity reactions.

⭐⭐⭐⭐⭐ VIDEO OF GUAIFENESIN/MUCINEX (DRUG)

Source: The content of this active ingredient has been written taking into account the clinical and molecular information of all medicines authorised and marketed in the United States under the Unique Ingredient Identifier (UNII) by the Substance Registration System (SRS) of the Food and Drug Administration (FDA) and the United States Pharmacopeia (USP).

In order to know in detail the information authorized by the FDA for each drug, you should consult the corresponding medication guide authorized by the FDA.

Resources:

UNII: 495W7451VQ
ChemIDplus
DrugPortal
PubChem CID: 3516
NCI Thesaurus: C29081

Editorial note Active Ingredients Online Editorial Team This article is prepared as educational medicine information for general readers. It is written to support understanding of active ingredients, medicine uses, possible side effects, precautions and safety-related questions.
Published: June 15, 2019 Updated: August 2, 2019 Educational content

Medical disclaimer

This content is for educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. Always ask a doctor, pharmacist or qualified healthcare professional before starting, stopping or changing any medicine.

Sources and verification

Medicine information can change by country, product formulation and official safety updates. For personal decisions, verify details with official medicine information and a qualified healthcare professional. These official resources can help readers check medicine safety information:

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Final note

Medicine information can change and may vary depending on country, product formulation, patient history and professional guidance. Always check official medicine information and ask a healthcare professional for personal medical questions.

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